USA: A recent study has suggested that statins could improve gum health and reduce the risk of heart disease. Could taking statins benefit your mouth in addition to your arteries? The study conducted in cell cultures showed that cholesterol-lowering drugs help to dampen the inflammation associated with periodontal disease by altering the behavior of macrophages, […]
In a nationwide study conducted in Sweden, researchers have discovered that administering antibiotics to newborns during their first week of life does not substantially heighten the risk of early-onset sepsis (EOS) or associated mortality. This finding comes as a significant reassurance to healthcare providers and parents, amid growing concerns regarding the overuse of antibiotics and […]
A recent study unveiled the cost-effectiveness of intravascular imaging-guided percutaneous coronary intervention (PCI) compared to conventional angiography-guided procedures. The findings were published in Circulation: Cardiovascular Quality and Outcomes reveal significant benefits for patients with complex coronary artery lesions. The RENOVATE-COMPLEX-PCI trial was conducted in Korea from May 2018 to May 2021 and examined the clinical […]
Canada: An analysis of the ISCHEMIA trial revealed that both invasive coronary angiography and coronary CT angiography (CCTA) add incremental information over baseline characteristics for predicting risk in stable coronary artery disease (CAD) patients. The findings, published in JACC: Cardiovascular Imaging, also show that invasive angiography addition on top of CCTA does not provide any […]
The drug minocycline, an antibiotic that also decreases inflammation, failed to slow vision loss or expansion of geographic atrophy in people with dry age-related macular degeneration (AMD), according to a phase II clinical study at the National Eye Institute (NEI), part of the National Institutes of Health. Dry AMD affects the macula, the part of […]
Integrase strand transfer inhibitors (INSTIs) are associated with more significant weight gain in women with HIV (WWH) compared to men with HIV. Menopausal transition leads to changes in body composition. A finding published in CROI, Conference on Retroviruses and Opportunistic Infections, mentioned that switching to INSTIs during the late peri- and postmenopausal phase is associated […]
No advantage of Laparoscopic surgery over open surgery in reducing the risk of bowel obstruction in complicated appendicitis suggests a new study published in the Journal of Pediatric Surgery. Complicated appendicitis is associated with a higher risk of postoperative complications, including adhesive bowel obstruction. This meta-analysis aims to investigate the difference in rates of postoperative […]
In a recent study, researchers have shed light on the efficacy of various treatments for a common symptom of overactive bladder (OAB) known as nocturia. The secondary analysis study found that for women with nocturia of at least 2 voids per night, treatment with anticholinergic medication, onabotulinum toxin A (BTX) (either 100 or 200 units), […]
It has been suggested that non-pharmaceutical approaches, such as the Buteyko breathing technique (BBT), be implemented to support traditional asthma therapy. However, the evidence regarding their effectiveness needs to be more consistent. A European Journal of Medical Research study has concluded that BBT is clinically effective. Despite the significant reduction of respiratory pharmacotherapy, improved symptom […]
Two commonly prescribed medications for gout treatment are febuxostat and benzbromarone. However, their clinical efficacy remains a subject of debate. A European Review for Medical and Pharmacological Sciences study concluded that Febuxostat significantly benefits renal function-related indexes, including the estimated glomerular filtration rate (eGFR), Cr, and blood urea nitrogen (BUN). In contrast, benzbromarone is more […]