USA: A secondary analysis of a randomized clinical trial (RCT) published as a research letter in JAMA Network Open has shed light on the effect of ergocalciferol, an inactivated vitamin D analog, on β-cell function in new-onset type 1 diabetes (T1D). The researchers showed that high-dose ergocalciferol, also known as vitamin D2, may help preserve […]
Replacing sugar with artificial and natural sweeteners in foods does not make people hungrier-and also helps to reduce blood sugar levels, a significant new study has found. The double blind randomised controlled trial found that consuming food containing sweeteners produced a similar reduction in appetite sensations and appetite-related hormone responses as sugary foods – and […]
A study from Karolinska Institutet published in the journal PLOS Medicine has revealed a bidirectional link between premenstrual disorders and perinatal depression. Acccording to the study, Women with premenstrual syndrome (PMS) or premenstrual dysphoric disorder (PMDD) have a higher risk of perinatal depression. Conversely, women with perinatal depression have a higher risk of developing premenstrual […]
Prosthetic loosening and infection are still common complications after joint replacement. Over the past few years, single-photon emission computed tomography–computed tomography (SPECT/CT) was widely used and showed unique value based on the combination of anatomic and metabolic information of foci. However, its performance in differentiating between prosthetic loosening and periprosthetic infection after joint replacement is […]
USA: In a self-controlled case series of 11,000 Medicare beneficiaries age 65 or older, the primary analysis showed no evidence of a significantly increased risk of stroke during the days immediately following the administration of either brand of the COVID-19 bivalent vaccine. “In the Medicare beneficiaries who experienced stroke following the administration of either brand […]
New research to be presented at this year’s European Congress on Obesity in Venice, Italy (12-15 May) shows that having obesity in childhood is associated with a more than doubling of the risk of later developing multiple sclerosis. The study is by Professor Claude Marcus and Associate Professor Emilia Hagman, Karolinska Institutet, Stockholm, Sweden, and […]
China: A recent meta-analysis published in the Journal of the European Academy of Dermatology and Venereology has shown an association between passive smoking during pregnancy and an increased risk of eczema development in offspring. Atopic dermatitis (eczema), a condition that causes dry, itchy, and inflamed skin, is common worldwide. Several studies have explored the modifiable […]
USA: A recent five-year study published in the Annals of Surgery has shed light on the effect of lower extremity nerve decompression in patients with painful diabetic peripheral neuropathy (DPN). “Although nerve decompression was tied to reduced pain, the benefit of surgical decompression requires further investigation since a placebo effect may be responsible for part […]
China: A recent Mendelian randomization (MR) study published in Frontiers in Medicine has shed light on the causal effect of high blood pressure (BP) and triglyceride (TG) on IgA nephropathy. The study revealed high BP and triglyceride as risk factors causally connected with immunoglobulin A nephropathy (IgAN), of which high BP was strongly related to […]
Only a very small percentage of neurons show changes after an epileptic seizure in mice, but these alterations can be permanent and trigger future seizures that can affect the whole brain and lead to impaired cognition, like memory and learning, according to new research from the Perelman School of Medicine at the University of Pennsylvania. […]