Entries by aaron

NAFLD tied to brain damage in patients with type 2 diabetes without cognitive impairment: Study

China: A recent study has suggested that controlling lipid levels, blood glucose levels, and abdominal obesity may reduce brain damage in patients with type 2 diabetes and non-alcoholic fatty liver disease (NAFLD). The findings, published in Diabetes, Obesity and Metabolism, provide novel insights into neuroimaging correlates for underlying pathophysiological processes inducing brain damage in patients […]

FDA approves Fabhalta as oral treatment for paroxysmal nocturnal hemoglobinuria

The US Food and Drug Administration has approved Fabhalta (iptacopan) as first oral monotherapy for adults suffering from paroxysmal nocturnal hemoglobinuria (PNH). PNH is a rare and chronic blood disorder where red blood cells are prone to premature destruction by the complement system. Despite prior anti-C5 treatments, a good number of patients with PNH still […]

Prenatal maternal inflammation tied to ADHD diagnosis by age 10

The available preclinical and registered data indicate that maternal inflammation during pregnancy may impact early neurodevelopment in offspring. However, there is limited clinical evidence of the risk of abnormal neurodevelopment in children later in life. In the population-based COPSAC2010 mother-child cohort, a team of researchers examined the relationship between maternal inflammation levels during pregnancy and […]

Cancer antigen-125 useful biomarker for preeclampsia severity?

India: A recent case-control study published in The Journal of Obstetrics and Gynecology of India explored the potential of cancer Antigen-125 (CA-125) as a biomarker for predicting and correlating with the severity of preeclampsia.  The researchers found higher levels of serum CA-125 in the severe preeclampsia group versus the normotensive and non-severe preeclampsia group, but […]

Treating Pituitary Apoplexy: Medical Management Versus Surgery

The first prospective study comparing outcomes in patients with pituitary apoplexy-sudden bleeding or death of a pituitary tumor-found that individuals managed medically fared as well as those treated surgically in the majority of cases. The multicenter international study, led by Cedars-Sinai investigators, was published in The Journal of Clinical Endocrinology & Metabolism. “This is the […]