Iran: A randomized clinical trial published in Pediatric Endocrinology Diabetes and Metabolism has shed light on the effect of oral probiotics on glycated haemoglobin levels (HbA1c) in children with type 1 diabetes mellitus (T1DM). The study showed no significant effect of consumption of oral probiotics on HbA1c levels in children with type 1 diabetes. Probiotics […]
New York: Pfizer Inc. has announced that the U.S. Food and Drug Administration (FDA) has accepted the company’s Biologics License Application (BLA) for its anti-tissue factor pathway inhibitor (anti-TFPI) candidate marstacimab for individuals living with hemophilia A or hemophilia B without inhibitors to Factor VIII (FVIII) or Factor IX (FIX). The European marketing authorization application (MAA) for […]
Italy: Platelet-rich plasma (PRP) intracavernosal injections may objectively improve or at least show a tendency for recovery in erectile function in men affected by primary organic erectile dysfunction (ED), a recent meta-analysis has revealed. The findings were published online in the International Journal of Impotence Research on November 22 2023. “The generalizability of these observations […]
USA: A recent study published in the Journal of Esthetic and Restorative Dentistry has shed light on the isolated effect of filler particle size on surface properties of experimental resin composites before and after toothbrush abrasion. The researchers showed a significant reduction in gloss of resin-based composites (RBCs) containing fillers with larger particle sizes. There […]
USA: Selected acute medications (e.g., ergots, anti-emetics, triptans) are associated with higher odds of user-rated positive response versus ibuprofen for patients with migraine, a recent study published in Neurology has shown. Using a big-data approach, the researchers analyzed patient-generated real-time records of 10 million migraine attacks, and simultaneous head-to-head comparisons of 25 acute migraine medications […]
A landmark study has shown that severe asthma can be controlled using biologic therapies, without the addition of regular high-dose inhaled steroids which can have significant side effects. The findings from the multinational SHAMAL study, published in The Lancet, demonstrated that 92% of patients using the biologic therapy benralizumab could safely reduce inhaled steroid dose […]
A recent systematic review and meta-analysis exploring the relationship between vitamin D levels and noninfectious uveitis have revealed a striking association. The findings suggest that individuals with vitamin D deficiency face more than a twofold increased risk of developing noninfectious uveitis compared to those without such deficiency. This study was published in the Autoimmunity Reviews […]
A study led by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine suggests that CAR-T immunotherapy remains a viable option for patients who have lymphoma that goes into remission before the cell therapy begins. While the study doesn’t answer the question of whether cell therapy in remission is […]
A recent investigation examined the combined influence of metabolic syndrome (MetS) and obesity on markers of early atherosclerosis—carotid artery intima media thickness (cIMT) and adventitial diameter (AD). This study was published in the Menopause journal by Leis and colleagues. Carotid ultrasound assessments conducted as part of the Study of Women’s Health Across the Nation (SWAN) […]
New Delhi: The drug major AstraZeneca has got approval from the Subject Expert Committee (SEC) functional under the Central Drug Standard Control Organisation (CDSCO) to conduct the trial of the Rilvegostomig (AZD2936) concentrate for solution for infusion to assess the efficacy and tolerability of rilvegostomig compared to placebo in combination with investigator’s choice of chemotherapy […]