Recent study unveiled important findings about the impact of valproate (VPA) use on the brain volume of individuals with idiopathic generalized epilepsy. The crucial results of the extensive study were published in Epilepsia Journal. The study employed voxel-based morphometry on magnetic resonance imaging (MRI) and focused on 112 patients currently using VPA (VPA+ group), 81 […]
Community-acquired pneumonia (CAP) is a leading cause of hospitalization and death. Timely antibiotic treatment is crucial to prevent complications like bacteremia, sepsis, organ failure, and death. Initial treatment is often empiric, and an uncertain or delayed diagnosis can lead to broad-spectrum antibiotic use. This contributes to adverse effects, such as Clostridioides difficile infection and super-infections […]
In a breakthrough study focusing on older veterans with chronic kidney disease (CKD), researchers have discovered a potential game-changer in the form of statin initiation. The study, employing a target trial emulation design, aimed to investigate the impact of statin use on all-cause mortality and major adverse cardiovascular events (MACE) in veterans aged over 65 […]
The preclinical research indicates that aspirin may play a role in slowing the progression of abdominal aortic aneurysms (AAAs) and averting their rupture. However, human studies are scarce to demonstrate the clinical advantages of aspirin in treating AAA. In a recent retrospective study of a clinical cohort of 3435 patients with objectively measured changes in […]
High resting heart rate may independent risk factor for end-stage renal disease suggests a new study published in the Journal of the American Heart Association. The relationship between resting heart rate (RHR) and the risk of end‐stage renal disease (ESRD) among those without cardiovascular disease remains unclear. We aim to establish temporal consistency and elucidate […]
A new phase 4 study published in The Journal of Obstetrics and Gynecology found elagolix 150 mg monotherapy taken once-daily to solve heavy menstrual bleeding associated with uterine leiomyomas were the safe and effective. This offers promise to premenopausal patients aged 18–51 years. This randomized, double-blind, placebo-controlled study assessed a total of 82 patients, with […]
New Delhi: Noting that the apathetic approach of the hospital and its doctors towards the gravity of the ailment raises a presumption as regards to the failure of treating doctors in clinical judgment and choosing the right course of action in time, the Delhi State Consumer Disputes Redressal Commission has upheld the District Forum’s order […]
USA: Exposure to per- and polyfluoroalkyl substances (PFAS) is associated with lower bone mineral density (BMD) in adolescence and young adulthood, critical periods for bone development, which may have implications on future bone health and osteoporosis risk in adulthood, a recent study has found. PFAS manufactured chemicals used in products such as food packaging and […]
Glucocorticoid effective option for preventing Postoperative delirium among patients undergoing major non-cardiac surgery suggests a new study published in the BMC Anesthesiology. The effects of intravenous glucocorticoids on postoperative delirium (POD) in adult patients undergoing major surgery remain controversial. Therefore, we conducted this meta-analysis to assess whether intravenous glucocorticoids can decrease POD incidence in the […]
The pharma companies and medical associations might need to disclose in the future the money they spend per doctor in conferences, a recent media report by The Print has stated. Recommendations in this regard were made by a high-level government panel set up to review the Uniform Code of Pharmaceutical Marketing Practices (UCPMP). Apart from […]