The US Food and Drug Administration has approved Fabhalta (iptacopan) as first oral monotherapy for adults suffering from paroxysmal nocturnal hemoglobinuria (PNH). PNH is a rare and chronic blood disorder where red blood cells are prone to premature destruction by the complement system. Despite prior anti-C5 treatments, a good number of patients with PNH still […]
A recent study delving into the interplay between dietary intake of polyunsaturated fatty acids (PUFA) and family history in relation to cardiovascular disease (CVD) risk has uncovered a significant association. Researchers have found in a new study that Low PUFA intake may magnify risk of developing CVD among people with family history of heart disease. […]
Placement of 6-mm implants as good as 11-mm implants for combined maxillary sinus floor augmentation suggests a new study published in the Clinical Oral Implants Research. A study was done to compare the clinical performance of single crowns in the posterior maxilla supported by either 11-mm long implants combined with maxillary sinus floor augmentation (MSFA) […]
The available preclinical and registered data indicate that maternal inflammation during pregnancy may impact early neurodevelopment in offspring. However, there is limited clinical evidence of the risk of abnormal neurodevelopment in children later in life. In the population-based COPSAC2010 mother-child cohort, a team of researchers examined the relationship between maternal inflammation levels during pregnancy and […]
China: A recent study published in Diabetes Therapy showed increased odds of diabetic kidney disease (DKD) in subjects with diabetes having poor nutritional parameters and high body fat. “Nutritional parameters and body fat were strongly associated with and considerably contributed to DKD presence, indicating that nutrition and body fat might be promising markers representing a […]
India: A recent case-control study published in The Journal of Obstetrics and Gynecology of India explored the potential of cancer Antigen-125 (CA-125) as a biomarker for predicting and correlating with the severity of preeclampsia. The researchers found higher levels of serum CA-125 in the severe preeclampsia group versus the normotensive and non-severe preeclampsia group, but […]
The first prospective study comparing outcomes in patients with pituitary apoplexy-sudden bleeding or death of a pituitary tumor-found that individuals managed medically fared as well as those treated surgically in the majority of cases. The multicenter international study, led by Cedars-Sinai investigators, was published in The Journal of Clinical Endocrinology & Metabolism. “This is the […]