A new study found increased coronary vessel wall thickness that was significantly associated with impaired diastolic function in asymptomatic, middle-aged individuals living with HIV. The study was published in Radiology: Cardiothoracic Imaging, a journal of the Radiological Society of North America (RSNA). According to the World Health Organization, approximately 39 million people were living with […]
Preemptive use of corticosteroids enhances the success of local anaesthesia among patients undergoing endodontic therapy suggests a study published in the Journal of Endodontics. Chronic inflammation in irreversible pulpitis leads to heightened sensitivity of nociceptive receptors, resulting in persistent hyperalgesia. This poses significant challenges in achieving effective anesthesia for patients with irreversible pulpitis. Various anesthetic […]
Researchers at The University of Texas MD Anderson Cancer Center showed that altering the sequence of breast cancer treatment to administer radiation before mastectomy allowed for concurrent breast reconstruction surgery, which reduced the number of operations required, minimized treatment delays and improved patient satisfaction. The Phase II trial results, published in JAMA Network Open, evaluated […]
Mechanical and oral antibiotic bowel preparation may reduce morbidity in patients undergoing elective rectal resection suggests a new study published in the JAMA. Surgical site infections (SSIs)—especially anastomotic dehiscence—are major contributors to morbidity and mortality after rectal resection. The role of mechanical and oral antibiotics bowel preparation (MOABP) in preventing complications of rectal resection is […]
Neurological complications have emerged as a significant concern in patients with Coronavirus Disease 2019 (COVID-19). A recent retrospective cohort study investigated the long-term outcomes of patients with and without neurological manifestations during their initial COVID-19 hospitalization. This study was published in PLoS Medicine journal. The study was conducted by Anna E. and colleagues. The study […]
Inhaled treprostinil cuts mortality among patients of pulmonary hypertension associated with interstitial lung disease suggests a study published in the BMJ thorax. A post-hoc analysis of the INCREASE trial and its open-label extension (OLE) was performed to evaluate whether inhaled treprostinil has a long-term survival benefit in patients with pulmonary hypertension associated with interstitial lung […]
China: A multicenter retrospective cohort study has revealed an association between longer serum phosphorus time in range and a lower mortality risk among peritoneal dialysis patients. The findings, published in BMC Nephrology, highlight the importance of maintaining serum phosphorus levels within 1.13–1.78 mmol/L for peritoneal dialysis patients. Mineral bone disease (MBD) is a common complication […]
China: A recent study published in the Journal of Neurosurgery has shown an association of moderate and severe persistent postoperative hyperglycemia with an increased mortality risk compared with normoglycemia in patients undergoing an elective craniotomy. The association was observed regardless of whether patients had preoperative hyperglycemia. The impact of persistent postoperative hyperglycemia after craniotomy has […]
The recent press release from a prominent biopharmaceutical company, LENZ Therapeutics, Inc. unveiled promising findings from its Phase 3 CLARITY study making a significant stride forward in the treatment of presbyopia. The study evaluated two formulations of aceclidine, LNZ100 and LNZ101 by demonstrating their potential to enhance the near vision in individuals with presbyopia. Presbyopia […]
New Delhi: Pharmaceutical major Eli Lilly has got marketing authorization from the Subject Expert Committee (SEC) functional under the Central Drug Standard Control Organisation (CDSCO) for Mirkizumab Injection 300mg/15mL solution in vial and 100mg/mL solution in Prefilled Syringe (PFS) indicated for the treatment of moderate to severe active ulcerative colitis in adult. This came after […]