Denmark: An arterial oxygen pressure (PaO2) target of 60 mm Hg versus 90 mm Hg led to more days alive without support in intensive care unit (ICU) patients with COVID-19 and severe hypoxemia, findings from HOT-COVID Randomized Clinical Trial have shown. The randomized trial, including 726 patients, found that targeting a Pao2 of 60 mm […]
A simple urine test can more than halve the number of cystoscopies necessary to follow up high-risk bladder cancer patients, new research has found. Cystoscopies involve inserting a flexible probe through the urethra into the bladder, which allows a clinician to look at the bladder lining for signs of cancer. While they are predominantly safe […]
Priovant Therapeutics recently unveiled promising results from the NEPTUNE Phase 2 study by testing the efficacy of brepocitinib in patients with non-anterior non-infectious uveitis (NIU) which can lead to severe visual impairment. This study highlights the potential of brepocitinib to revolutionize treatment paradigms in autoimmunity by specifically targeting a condition with few effective treatments currently […]
In the largest study to date on the subject, researchers found no evidence to support a causal link between acetaminophen use during pregnancy and increased risk of autism, ADHD and intellectual disability in children. The findings, using data from a nationwide cohort of over 2.4 million children born in Sweden, including siblings not exposed to […]
The US Food and Drug Administration has cleared Modius Stress to treat generalized anxiety disorder. Made by Neurovalens is a non-invasive electrical stimulation device for treatment of anxiety. Modius Stress becomes company’s second product cleared for use in US Neurovalens, a global leader in non-invasive neuro-technology, has received medical device clearance from the US Food […]
New research being presented at this year’s ESCMID Global Congress (formerly ECCMID) in Barcelona, Spain (27-30 April) suggests that the free-to-use, widely accessible ChatGPT could be an effective tool to help reduce vaccine hesitancy among the general public, as well as providing helpful advice on sexually transmitted infections (STIs) in conjunction with sexual health clinics, […]
AI system improves accuracy of CBCT images for implant placement, third molar extraction and orthognathic surgery suggests a new study published in the Journal of Dentistry. A study was done to develop a deep learning-based system for precise, robust, and fully automated segmentation of the mandibular canal on cone beam computed tomography (CBCT) images. The […]
A new technology using ultralow temperature cryoablation (ULTC) has eliminated clinical ventricular tachycardia (VT) in 94% of patients. The late-breaking science is presented at EHRA 2024, a scientific congress of the European Society of Cardiology (ESC). VT is a leading cause of sudden death in patients with heart failure and a reduced ejection fraction.2 Approximately […]
Esophageal squamous cell carcinoma (ESCC) accounts for around 90% of esophageal cancers, especially in East Asia. New findings in The American Journal of Pathology, published by Elsevier, indicate that periostin, or POSTN, promotes ESCC progression by enhancing cancer and stromal cell migration in cancer-associated fibroblasts (CAFs). Therefore, it may be a novel therapeutic target for […]
USA: A recent meta-analysis including 8 studies has suggested a small, albeit significant, reduced risk for early posttraumatic seizures (PTS) for mild to moderate traumatic brain injury (TBI) of seizure prophylaxis. The researchers suggest weighing the small absolute risk reduction against the risks of prescribing antiseizure medications. The findings were published online in JAMA Neurology […]