Mumbai: Global pharma major Lupin Limited has announced the launch of first generic version of Oracea (Doxycycline Capsules, 40 mg), in the United States, after having received an approval from the United States Food and Drug Administration (U.S. FDA). Read also: Lupin gets USFDA nod for generic equivalent of Oracea Capsules Doxycycline Capsules, 40 mg is […]
South Korea: Adjunctive pioglitazone therapy in type 2 diabetes mellitus (T2DM) inadequately controlled with dapagliflozin and metformin yielded considerable metabolic benefits, glycemic improvement, and a low hypoglycemia risk, a phase 3 trial showed. The findings were published online in Diabetes, Obesity and Metabolism on February 29, 2024. The researchers, however, suggest weighing its advantages against […]
China: A two-sample Mendelian randomization (MR) study provides genetic evidence supporting the anti-inflammatory effects of sodium-glucose cotransporter 2 (SGLT-2) inhibitors and their beneficial impact in reducing heart failure (HF) risk. CXCL10 emerged as a potential mediator, offering a novel intervention pathway for the treatment of heart failure. The findings were published online in Cardiovascular Diabetology […]
Withdrawing aspirin one month after percutaneous coronary intervention (PCI) in high-risk heart patients and keeping them on ticagrelor alone safely improves outcomes and reduces major bleeding by more than half when compared to patients taking aspirin and ticagrelor combined (also known as dual antiplatelet therapy or DAPT), which is the current standard of care. These […]
Brazil: A recent study has revealed that adjuvant hyperbaric oxygen therapy (HBOT) may provide some benefits in treating pyoderma gangrenosum patients, particularly those with multiple comorbidities precluding them from receiving more traditional treatments. The study findings were published online in the Journal of the European Academy of Dermatology and Venereology on March 20, 2024 “After […]
Hypertriglyceridemia, or high levels of lipids (fats) in the blood, increases the risk of heart attack, stroke and acute pancreatitis. Currently available medications, including statins, ezetimibe, fibrates and prescription omega 3 fatty acids, typically lower triglyceride levels by anywhere from below 10% to up to 40%. These therapies help, but they are not enough to […]
USA: A recent study published in JAMA Surgery reports US liver transplant outcomes after normothermic regional perfusion (NRP) versus standard super rapid recovery. The findings suggest that NRP improves controlled donation after circulatory death (DCD) liver allograft outcomes and holds the potential to increase DCD organ use. “The multicenter cohort study comprisng136 livers recovered with […]
Austria: Findings from a recent meta-analysis published in JAMA Oncology support the integration of prostate magnetic resonance imaging (MRI) in prostate cancer (PCa) screening to improve the balance of patient harms and benefits. The systematic review and meta-analysis of 80 114 screened men from 12 studies revealed that MRI-based screening is associated with a reduced […]
A new study presented at the European Psychiatric Association Congress 2024 reveals a significant association between prenatal cannabis use disorder (CUD) and an increased risk of neurodevelopmental disorders in offspring, including attention deficit hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and intellectual disability (ID). Cannabis remains by far the most consumed illicit drug in Europe. […]
Poland: Plasma aldosterone levels do not predict 28-day mortality in patients treated for COVID-19 in the ICU, a recent study published in Scientific Reports has revealed. Other factors, including the patient’s age, C-reactive protein (CRP), or creatinine contribute to the prognosis and severity of the disease. In this study, the researchers attempted to find an […]