Entries by aaron

Transarterial chemoembolization and sorafenib combo improves survival in hepatocellular patients with PVTT: JAMA

China: A recent study showed a longer recurrence-free survival and overall survival with the combination of sorafenib and transarterial chemoembolization as postoperative adjuvant therapy among patients with hepatocellular carcinoma with portal vein tumor thrombus (PVTT). “The randomized clinical trial comprising 158 patients showed that both the median recurrence-free survival and median overall survival were significantly […]

Urine test halves painful procedures in bladder cancer follow up, new trial shows

A simple urine test can more than halve the number of cystoscopies necessary to follow up high-risk bladder cancer patients, new research has found. Cystoscopies involve inserting a flexible probe through the urethra into the bladder, which allows a clinician to look at the bladder lining for signs of cancer. While they are predominantly safe […]

Brepocitinib Demonstrates Promising Phase 2 Results in Uveitis Treatment

Priovant Therapeutics recently unveiled promising results from the NEPTUNE Phase 2 study by testing the efficacy of brepocitinib in patients with non-anterior non-infectious uveitis (NIU) which can lead to severe visual impairment. This study highlights the potential of brepocitinib to revolutionize treatment paradigms in autoimmunity by specifically targeting a condition with few effective treatments currently […]

FDA clears non invasive device for treatment of anxiety

The US Food and Drug Administration has cleared Modius Stress to treat generalized anxiety disorder. Made by Neurovalens is a non-invasive electrical stimulation device for treatment of anxiety. Modius Stress becomes company’s second product cleared for use in US Neurovalens, a global leader in non-invasive neuro-technology, has received medical device clearance from the US Food […]

ChatGPT could help reduce vaccine hesitancy and provide helpful advice on STIs, suggests study

New research being presented at this year’s ESCMID Global Congress (formerly ECCMID) in Barcelona, Spain (27-30 April) suggests that the free-to-use, widely accessible ChatGPT could be an effective tool to help reduce vaccine hesitancy among the general public, as well as providing helpful advice on sexually transmitted infections (STIs) in conjunction with sexual health clinics, […]

First-in-human study demonstrates reduction of hard-to-reach ventricular tachycardias

 A new technology using ultralow temperature cryoablation (ULTC) has eliminated clinical ventricular tachycardia (VT) in 94% of patients. The late-breaking science is presented at EHRA 2024, a scientific congress of the European Society of Cardiology (ESC). VT is a leading cause of sudden death in patients with heart failure and a reduced ejection fraction.2 Approximately […]

Periostin shows promise to help fight a common form of esophageal cancer

Esophageal squamous cell carcinoma (ESCC) accounts for around 90% of esophageal cancers, especially in East Asia. New findings in The American Journal of Pathology, published by Elsevier, indicate that periostin, or POSTN, promotes ESCC progression by enhancing cancer and stromal cell migration in cancer-associated fibroblasts (CAFs). Therefore, it may be a novel therapeutic target for […]