HIV (Human Immunodeficiency Virus) remains one of the deadliest infectious diseases and developing an HIV vaccine remains a global health priority. Although new treatment and prevention options have changed the HIV landscape for the better, an HIV vaccine is still needed to bring a true end to the HIV pandemic. The Indian epidemic is concentrated […]
A recent first-in-human clinical trial, Cryocure-VT, has unveiled an amazing advancement in the treatment of scar-dependent ventricular tachycardias (VTs). The trial investigated the safety and efficacy of a novel ultra-low-temperature cryoablation (ULTC) catheter system utilizing nitrogen cryogen at a chilling -196°C, showcasing remarkable potential in addressing this cardiac arrhythmia. The trial results were published in […]
USA: A recent study has revealed a higher average A1C and diabetes duration to be significant factors in the risk of developing distal symmetric polyneuropathy (DSPN). Results from the Diabetes Prevention Program Outcome Study, published in Diabetes Care, informed the conclusions. Distal symmetrical polyneuropathy (DSPN) is a common complication associated with diabetes mellitus, characterized by […]
USA: In a pilot study published in Vascular Medicine, etidronate was shown to slow the progression of vascular calcification in the lower extremities for patients with arterial calcification due to deficiency of CD73 (ACDC). The researchers found that etidronate treatment slowed the progression of further vascular calcification in the lower extremities as measured by computed […]
China: A prospective observational study involving 51 avulsed and replanted immature permanent teeth showed a pulse oximeter test as an effective tool to evaluate the pulp status. “An oxygen saturation test is a reliable diagnostic method to evaluate pulp status of avulsed teeth as early as 2 weeks after replantation,” the researchers wrote in the […]
Switzerland: A recent study published in Annals of Intensive Care has shown a significant association between fluid accumulation and major adverse kidney events in critically ill patients’ first 30 days after ICU admission (MAKE30). This association was shown to be independent of pre-existing chronic kidney disease (CKD) and strongest in patients with acute kidney injury […]
Rutgers Health researchers have found that hypertensive disorders in pregnancy are strongly associated with fatal cardiovascular disease for up to a year after birth. Among the hypertensive disorders that cause dangerously high blood pressure during pregnancy — chronic hypertension, gestational hypertension, preeclampsia without severe features, preeclampsia with severe features, superimposed preeclampsia and eclampsia — all […]
Wide-Awake Local Anaesthesia No Tourniquet (WALANT), a groundbreaking anaesthetic technique resurging in practice, warrants a comprehensive safety analysis for informed adoption. Jad Lawand et al conducted a study to identify complications/side effects of WALANT upper limb procedures through a systematic review and meta-analysis. A PROSPERO-registered study was performed with strict adherence to PRISMA guidelines. Embase, […]
In a significant breakthrough, a recent multicenter retrospective study has shed light on the postoperative outcomes of ulcerative colitis (UC) patients treated with tofacitinib versus biologics prior to total colectomy. Researchers found that Preoperative tofacitinib was as safe as biologics in patients with UC undergoing colectomy. The findings, published in The American Journal of Gastroenterology offers valuable […]
AstraZeneca’s FASENRA® (benralizumab) is now approved by the US Food and Drug Administration (FDA) for add-on maintenance treatment for patients with severe asthma aged 6 to 11 with an eosinophilic phenotype.1 FASENRA was first approved in 2017 as an add-on maintenance for the treatment of severe eosinophilic asthma (SEA) in patients aged 12 and older.1 […]