Researchers have found in a new study that exposure to immune checkpoint inhibitors (ICIs) during pregnancy did not demonstrate an increased risk of specific adverse outcomes overall among mother or fetus. The cohort study delved into the risks associated with immune checkpoint inhibitor (ICI) exposure during pregnancy, addressing concerns about maternal and fetal health outcomes. […]
New research published today in the journal Cellular and Molecular Gastroenterology and Hepatology sheds light on disease mechanisms common to irritable bowel syndrome (IBS) and cardiovascular diseases (CVD). Led by Dr Leticia Camargo Tavares, a Postdoctoral Fellow at the Hypertension Research Laboratory within Monash University’s School of Biological Sciences, the study reveals novel insights into […]
A new study published today in the American Journal of Infection Control (AJIC) demonstrates the use of a simple pre-surgical infection prevention protocol to prevent dangerous post-surgical infections. Researchers performed this investigation at the Soroka University Medical Center in Israel. Surgical site infections (SSIs) are a type of healthcare-associated infection with deadly consequences for some […]
A new study has revealed that self-administered acupressure (SAA), when combined with brief knee health education, can significantly reduce knee pain in middle-aged and older adults suffering from osteoarthritis (OA). The study results were published in the journal JAMA Network Open. The effectiveness of self-administered acupressure (SAA) for reducing pain in knee osteoarthritis (OA) among […]
Researchers have found that the use of dupilumab, a human monoclonal antibody targeting the IL-4 alpha receptor, is associated with an increased risk of cutaneous T cell lymphoma (CTCL) in patients with moderate to severe atopic dermatitis (AD), according to a study published in the Journal of the American Academy of Dermatology. The study was […]
USA: A recent study published in JAMA Network Open has suggested an association of clonal hematopoiesis (CH) risk score with overall and disease-specific mortality in older adults with CH. Thus, the CH risk score (CHRS) could be used to identify patients with CH who require more intensive surveillance. The cohort study included 3871 individuals without […]
Flow cytometry useful alternative to microscopy for differentiation of bronchoalveolar lavage fluid leukocytes suggests a study published in the Chest. Microscopy is currently the gold standard to differentiate BAL fluid (BALF) leukocytes. However, local expertise for microscopic BALF leukocyte differentiation is often unavailable in clinical practice. A new automated flow cytometric method for BALF leukocyte […]
USA: The American College of Physicians (ACP) has released a review of performance measures designed to evaluate the quality of care for those with major depressive disorder (MDD). They found only one of eight measures relevant to internal medicine physicians to be valid. The paper, published in Annals of Internal Medicine, presents a review of […]
An effective treatment for chronic wounds that does not involve antibiotics, but an ionised gas to activate a wound dressing, has been developed by a team of international scientists. The treatment involves the plasma activation of hydrogel dressings (that are commonly used in wound dressings) with a unique mix of different chemical oxidants that are […]
Loneliness is a significant biopsychosocial stressor with a mortality risk comparable to smoking more than 15 cigarettes a day and more harmful than alcoholism, obesity and lack of physical activity. Despite its harmful effects, interventions to address the discrepancy between desired and actual social interaction are few and limited. In a new study, Regenstrief Institute […]