The U.S. Food and Drug Administration (FDA) has approved the immunotherapy-boosting drug N-803, which is marketed under the brand name Anktiva, to be used in combination with the immunotherapy Bacillus Calmette-Guerin (BCG) for the treatment of patients with BCG-unresponsive non–muscle-invasive bladder cancer. The decision was based on results of the QUILT 3.032 clinical trial, which […]
The US Food and Drug Administration (FDA) has approved over-the-counter naloxone hydrochloride nasal spray for emergency treatment of opioid overdose. Amneal’s Naloxone HCI Nasal Spray, manufactured in the U.S., is a generic equivalent to OTC NARCAN® HCI Nasal Spray, a medication that is widely used to help treat drug overdose from opioids, including heroin, fentanyl […]
Turkey: In a groundbreaking experimental study, researchers have compared the effectiveness of intratympanic oxytocin and dexamethasone in combating cisplatin-induced ototoxicity, a common side effect of cisplatin chemotherapy. The study, published in the Indian Journal of Otolaryngology and Head & Neck Surgery, revealed that intratympanic oxytocin may be an option that can be used in the […]
A recent study found that the combination of acetaminophen (APAP) and a new formulation of ibuprofen, also called as ibuprofen sodium dihydrate (ISD), does not improve pain relief for patients with severe dental pain linked to apical periodontitis when compared to ISD alone. The critical findings were published in the Journal of Endodontics. This double-blind, […]
South Korea: In a critical advancement for stroke care, a recent study has validated the Practical Assessment of Dysphagia (PAD) test as a reliable tool for evaluating swallowing difficulties in stroke patients. The findings, published in the Dysphagia journal, underscore the importance of accurate and efficient dysphagia assessment in improving patient outcomes post-stroke. The study […]
USA: In a noteworthy development in the field of gastroenterology, a recently published case report has shed light on a rare but potentially significant association between the use of progesterone-only contraceptives and the development of ischemic colitis, a condition characterized by inflammation and injury to the colon due to reduced blood flow. In the case […]
Compared with people without opioid use disorder, those with opioid use disorder were less likely to receive palliative care in clinics and in their homes, and were dying at younger ages of causes other than opioid use, according to new research published in CMAJ (Canadian Medical Association Journal). “The majority of conversations about the opioid […]
In a comprehensive multicenter randomized clinical trial, researchers have explored the effectiveness of therapeutic hypothermia in preventing delayed graft function in kidney transplants from low-risk, non-pumped donors after brain death. The study, spanning from August 10, 2017, to May 21, 2020, across four Organ Procurement Organizations in the United States, aimed to address a crucial […]
USA: A longitudinal study has revealed that indoor allergen exposure to pests like mice and cockroaches (but not dogs and cats) is linked with the occurrence of upper respiratory infections (URIs) and associated pulmonary outcomes in children with asthma. “Mouse allergen concentration (OR 1.58) and cockroach allergen concentration (OR 1.79) was associated with URI with […]
For patients undergoing carpometacarpal (CMC) joint surgery for treatment of thumb osteoarthritis, the use of online video instruction for postoperative hand therapy is associated with outcomes similar to in-person therapy visits – while substantially reducing travel time and distance, reports a clinical trial in The Journal of Bone & Joint Surgery. The journal is published […]