Obesity is a prevalent health concern, and effective weight loss interventions are crucial. However, sustaining weight loss over the long term poses significant challenges. Pragmatic and scalable interventions are needed to address this issue, especially in primary care settings where patients often seek guidance for weight management. A recent clinical trial aimed to evaluate the […]
Parkinson’s disease (PD) is a progressive neurodegenerative disorder affecting movement and quality of life in the elderly. The causes of PD remain unclear, though mitochondrial dysfunction, oxidative stress and neuroinflammation are implicated. Recent evidence suggests chronic conditions like chronic kidney disease (CKD) and related markers of renal dysfunction may be associated with higher PD risk. […]
In a discovery that could hasten treatment for patients with multiple sclerosis (MS), UC San Francisco scientists have discovered a harbinger in the blood of some people who later went on to develop the disease. In about 1 in 10 cases of MS, the body begins producing a distinctive set of antibodies against its own […]
Glaucoma effects around 70 million people worldwide and can cause irreversible loss of vision if not treated-but around half of those living with the condition are not aware of it. Usually developing slowly over time, many cases of glaucoma are only picked up during routine eye tests, by which time lasting damage may already have […]
Combination treatments with two or more blood pressure drugs can significantly reduce blood pressure in patients taking ibrutinib, according to a new study published in Blood Advances. Targeted drugs such as ibrutinib have improved outcomes for patients with cancers of the lymphatic system, but patients treated with ibrutinib and other drugs in its class often […]
Recent research paper investigates the association between Sequential Organ Failure Assessment (qSOFA) and 28-day mortality in intensive care unit (ICU) patients admitted for sepsis, focusing on different income settings. The study included 4980 patients from 343 ICUs and 22 countries, analyzing the association of qSOFA with early (3-day), medium (28-day), and late (90-day) mortality in […]
USA: A recent study published in Menopause has revealed a joint association of migraines and persistent vasomotor symptoms (VMS) with a greater risk of stroke and cardiovascular diseases, although the risk attenuates with adjustment for traditional CVD risk factors. Catherine Kim, Departments of Medicine, Obstetrics and Gynecology, and Epidemiology, University of Michigan, Ann Arbor, MI, […]
Researchers have found that intravenous tirofiban, administered within 24 hours of stroke onset, decreases the risk of early neurological deterioration in patients with acute noncardioembolic stroke compared to oral aspirin. The study’s findings suggest that tirofiban may be an effective alternative to traditional antiplatelet therapy without increasing the risk of symptomatic intracerebral hemorrhage. This study […]
Canada: A first-of-its-kind network meta-analysis (NMA) published in the Journal of Cosmetic Dermatology has shed light on the relative effect of monotherapy with 5-alpha reductase inhibitors and minoxidil for female pattern hair loss (PHL). For both agents, the efficacy appeared to be considerably dose-dependent. “Our findings can improve clinical guidelines and help dermatologists manage female […]
Recent findings from the Appendicitis Acuta II (APPAC II) trial indicated that treating uncomplicated acute appendicitis with just oral antibiotics may not be inferior to a combined regimen of intravenous and oral antibiotics. This study published in the Journal of American Medical Association offers critical look at the potential of antibiotic monotherapy to replace more […]