Over 11.76 lakh calls addressed through helpline, 53 Tele MANAS cells established: MoS Health informs Parliament

New Delhi: According to the National Mental Health Survey carried out by the Government in collaboration with the National Institute of Mental Health and Neurosciences (NIMHANS) in Bangalore, which encompassed 12 states across the country, the prevalence of mental disorders among adults aged 18 and older is approximately 10.6%, the Union Minister of State for Health Shri. Prataprao Jadhav informed the Lok Sabha recently.  

According to MoS Health, the Government launched a “National Tele Mental Health Programme” (NTMHP) on 10th October 2022, to improve access to quality mental health counselling and care services in the country. As of 23.07.2024, 36 States/ UTs have set up 53 Tele MANAS Cells and have started telemental health services. More than 11,76,000 calls have been handled on the helpline number.

Also read- Declining oral health may predict mental health issue including depression: Study

The Minister was responding to a series of questions raised by Parliament member Shri Raja A who sought to know whether the Government conducted any survey to find the percentage of people affected by mental illness in the country, if so, the details thereof; whether the access to mental health facilities and professionals is hindered by inadequate infrastructure and specialist doctors in rural areas, if so, the details thereof along with the steps taken in this regard, area-wise.

He also inquired whether any review has been made on the effectiveness of National Tele-Mental Health Programme which was launched two years back; and if so, the steps taken/proposed to be taken by the Government to make it more effective and popular in the rural areas in the country.

In response to these questions, MoS Health said that the Government is implementing the National Mental Health Programme (NMHP) to provide affordable and accessible mental healthcare facilities in the country. 

“The District Mental Health Programme (DMHP) component of the NMHP has been sanctioned for implementation in 767 districts for which support is provided to States/UTs through the National Health Mission. Facilities made available under DMHP at the Community Health Centre(CHC) and Primary Health Centre(PHC) levels include outpatient services, assessment, counselling/ psycho-social interventions, continuing care and support to persons with severe mental disorders, drugs, outreach services, ambulance services etc. In addition to the above services, there is a provision of 10-bed in-patient facility at the District level,” said the Minister. 

Further, the minister informed the parliament that  25 Centres of Excellence have been sanctioned to increase the intake of students in PG departments in mental health specialities as well as to provide tertiary-level treatment facilities under the tertiary care component of the National Mental Health Programme. Further, the Government has also supported 19 Government medical colleges/institutions to strengthen 47 PG Departments in mental health specialities. Mental Health Services are also provisioned for in 22 new All India Institute Of Medical Science (AIIMS). 

In addition to the above, the Government is also taking steps to strengthen mental healthcare services at primary healthcare level. The Government has upgraded more than 1.73 lakh Sub Health Centres (SHCs) and Primary Health Centres (PHCs) to Ayushman Arogya Mandirs. Mental health services have been added in the package of services under Comprehensive Primary Health Care provided at these Ayushman Arogya Mandirs. Operational guidelines on Mental, Neurological, and Substance Use Disorders (MNS) at Ayushman Arogya Mandirs have been released under the ambit of Ayushman Bharat.

“The Government is also augmenting the availability of manpower to deliver mental healthcare services in the underserved areas of the country by providing online training courses to various categories of general healthcare medical and para medical professionals through the Digital Academies, since 2018, established at the three Central Mental Health Institutes namely National Institute of Mental Health and Neuro Sciences, Bengaluru, Lokopriya Gopinath Bordoloi Regional Institute of Mental Health, Tezpur, Assam, and Central Institute of Psychiatry, Ranchi. 

Besides the above, the Government has launched a “National Tele Mental Health Programme” (NTMHP) on 10th October 2022, to improve access to quality mental health counselling and care services in the country. As on 23.07.2024, 36 States/ UTs have set up 53 Tele MANAS Cells and have started tele mental health services. More than 11,76,000 calls have been handled on the helpline number,” added the Minister. 

Also read- Central Council for Research in Ayurvedic Sciences operates 30 Research Institutes: MoS AYUSH

Powered by WPeMatico

Telangana Govt Hospital administers expired saline to patient

Adilabad: A government hospital in Telangana is facing controversy after it was reported that an expired saline solution was administered to a patient with viral fever.

A serious lapse in healthcare standards
came to light when the staff of the
Khanapur government Hospital allegedly administrated an expired saline to a
patient.

The patient, from Lingapur village of Nirmal district, who was suffering from
viral fever was admitted to the hospital on Friday morning.

Also Read:KIMS Cuddles Doctors treat 18-Month-Old girl for Chemical Pneumonitis after mosquito repellent Ingestion

According to the reports, a patient at the Khanapur
Government Hospital was given a saline solution that had expired. The
patient’s family noticed the expiration date on the saline bag, which has past
its validity period. Concerning the potential risks, they raised the matter
with the hospital authorities. Following this they replaced it with another
one. 

Speaking to The New Indian Express, District Medical and
Health Officer Dr. Rajendar, who visited the hospital after the issue came to
light, said that an inquiry is being carried out and action will be taken against the guilty. 

On the instructions of Khanapur MLA Vedma Bhojju, Municipal
Chairman R Sathyam has visited the hospital. He said that no lapses were found
during his visits and that these allegations were aimed at demoralizing the
hospital staff and tarnishing the reputation of state government hospitals.

Dr. Shiva Raju K, Head of the Department of Medicine at
KIMS, provided some clarity on the potential effects of expired saline.
According to him an expired saline solution generally loses its efficacy over
time and it wouldn’t be life-threatening unless a heavy dosage of expired
antibiotics was administered. He emphasized that the impact of using expired
saline would vary depending on the patient’s medical condition such as in case
of severe infections or treatment of cancer or other medical conditions.

Also Read:KIMS acquires 100 per cent stake in 200-bed ‘Queen’s NRI Hospital’ in Andhra Pradesh

Powered by WPeMatico

PET Imaging Reveals Risk Factors for Major Adverse Cardiac Events in Cardiac Sarcoidosis: Study

Canada: A recent study published on August 7 in JACC: Cardiovascular Imaging finds that PET imaging can help determine if patients with cardiac sarcoidosis are at an increased risk of major adverse cardiac events (MACE).

In a meta-analysis of existing cardiac PET studies, researchers discovered that abnormal FDG uptake and perfusion defects were especially predictive of adverse outcomes.

“This study advocates for the routine use of FDG-PET in cardiac sarcoidosis for risk stratification, as patients exhibiting specific features like right ventricular uptake may be at an elevated risk for future MACE,” Tahir S. Kafil, Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio, USA, and colleagues wrote.

Cardiac sarcoidosis, a condition characterized by granuloma formation in the heart, poses a substantial risk of serious complications, including heart failure, arrhythmias, and sudden cardiac death. Accurate risk stratification is crucial for managing these patients effectively. While positron emission tomography (PET) imaging is well-established for diagnosing cardiac sarcoidosis, its prognostic value and effectiveness in risk-stratifying patients for MACE are less understood.

To fill the knowledge gap, Nikolaos Tzemos, Western University, London, Ontario, Canada, and colleagues performed a systematic review and meta-analysis looking at the predictive value of PET imaging in patients with cardiac sarcoidosis.

For this purpose, the researchers reviewed current medical literature and aggregated data from 55 cardiac PET studies, which included 5,250 patients with cardiac sarcoidosis. These studies provided outcomes on various cardiovascular adverse events, such as death, arrhythmia, ventricular tachycardia, ventricular fibrillation, heart block, cardiomyopathy, and heart failure.

The search identified 3,010 records, of which 55 studies were selected for inclusion, representing 5,250 patients.

The following were the key findings:

  • Factors associated with MACE included the following: the combination of abnormal fluorodeoxyglucose (FDG) uptake and perfusion defect, which had an OR of 2.86; abnormal perfusion or FDG uptake, which had an OR of 2.69; abnormal FDG uptake, which had an OR of 2.61; focal abnormal right ventricular uptake, which had an OR of 6.27; and a lack of response to immunosuppression on serial PET, which had an OR of 8.43.
  • A QUIPS (Quality in Prognostic Studies) tool analysis found a low to moderate risk of bias, particularly given the small sample sizes in the individual studies.

In conclusion, the systematic review evaluated the predictive value of cardiac FDG PET imaging in CS. The risk of MACE was increased by factors such as a PET perfusion defect, increased FDG uptake, focal uptake in the right ventricle (RV), and a lack of therapeutic response observed in serial PET imaging.

“The studies exhibited a low to moderate risk of bias, particularly due to the small sample sizes. Despite the need for further research, PET imaging overall offers several valuable parameters for risk stratification,” the researchers concluded.

Reference:

Kafil, T. S., Shaikh, O. M., Fanous, Y., Benjamen, J., Hashmi, M. M., Jawad, A., Dahrouj, T., Abazid, R. M., Swiha, M., Romsa, J., Beanlands, R. S., Ruddy, T. D., Mielniczuk, L., Birnie, D. H., & Tzemos, N. (2024). Risk Stratification in Cardiac Sarcoidosis With Cardiac Positron Emission Tomography: A Systematic Review and Meta-Analysis. JACC: Cardiovascular Imaging. https://doi.org/10.1016/j.jcmg.2024.05.013

Powered by WPeMatico

MP DME releases Instructions, FAQs for State Level Joint NEET Counselling 2024, details

Madhya Pradesh- Through recent notices, the Directorate of Medical Education of Madhya Pradesh has
released Necessary instructions and Frequently Asked Questions for the candidates for State
Level Joint Counselling NEET UG 2024 admissions to MBBS and BDS courses.

All the interested candidates are advised to take note of thee following details:

Advisory
for candidates

1. All
state quota seats (MBBS/BDS) available in government and private/medical and
dental colleges of the state, including NRI quota seats available in private
medical/dental colleges. Madhya Pradesh State Level Joint Counselling NEET UG
2024-25 will be conducted on MP online portal 

2. All
eligible candidates of NEET UG 2024 who want to participate in the above counselling
are advised not to share their login ID and password, mobile number, e-mail ID,
bank account information and other related information with any other person.
Do not share, so that it is not misused.

3. Before
registration, carefully read the registration user manual and Madhya Pradesh
Medical Education Admission Rules 2018 and amendment rules dated 19 June 2019,
05 October 2021, amendment July 2022, amendment dated 10 May 2023 and amendment
02 July 2024 displayed on the website and portal of the Directorate.
Understand. In case of any doubt, please send your problem to the Directorate
of Medical Education Counselling on the e-mail mpugpgcounselling@gmail.com and
get it resolved. The candidate will be able to edit the entries in the
registration and profile till the prescribed time limit shown for registration
in the time table. After the closure of the registration window, there will be
no amendment in the registration for the first phase of counselling.

4. While
filling the bank details in the candidate profile at the time of registration,
ensure that the bank account is as follows:-

1- The bank account should be a savings
or current account.

2- The bank account should not belong to
a minor.

3- Bank account should be active as per
KYC (KYC compliant).

4- If it is a savings bank account, then
the savings bank account should be a normal savings bank where there is no
limit on maximum balance/credit in the account.

5. Pradhan Mantri Jan Dhan Yojana (PMJDY)
account and zero balance account are not valid.

5. The
candidate will be considered registered only when the candidate has deposited
the online fee of Rs 1100/- for registration and the candidate must have the
registration slip generated from the MP online portal. Registration fee is
non-refundable.

6. The
time of registration will not be extended due to any reason like network
failure, computer failure, technical error, power failure etc. Therefore,
candidates are advised to complete the registration process as soon as possible
within the time period and not wait till the last date of registration.

7. Except
the candidates admitted in the first phase and those candidates who have
resigned from the seat after taking admission in the first phase, other
candidates who, for any reason, wish to make amendments in the registration
done before the first phase counselling, should Before the second phase of
counselling, one last opportunity will be provided to make necessary amendments
in the registration within the stipulated time limit. After the expiry of the
prescribed time limit, no further opportunity will be given to the candidates.

8. The
process of all the stages of counselling is to be done online, hence the
candidate has to pay the advance amount at the time of registration, before
filling the new choice in the second stage and mop up stage counselling and the
prescribed fee of the institution at the time of admission. to be through.
Candidates can pay the prescribed fees from any account through net banking,
credit card, debit card and online RTGS/NEFT. A candidate can use more than one
net banking account, debit card or credit card for payment of fees. Keeping the
above in mind, candidates are advised to keep sufficient amount in their
accounts as per the prescribed fees of the institution to avoid problems
related to fee payment. Candidates should ensure that internet banking facility
is available in the bank account and increase the limit of transaction amount
done from the account. After the mop up phase For vacancies remaining vacant
due to any reason, the prescribed fee of the institution can be paid by the
candidate through any means at the time of admission in the stray vacancy
phase.

9. For
photo ID in the registration form, the candidate should submit his/her Voter ID
card/PAN card/Diving License Card/Passport or in case the above is not
available, 12th class admit card with photo or mark sheet/bank passbook/with
photo issued by the school. ID/Any photo ID issued by Government can be
uploaded.

10 After
registration, candidates will have to register their choices (choice filling)
within the specified time limit for admission as per the counselling schedule
shown earlier. At the time of choice locking, the candidate will have to pay
portal charge of Rs. 100/-, only after that the candidate will be able to get
the online receipt of his/her choice filling locking.

11. In the
first phase of counselling, only local resident candidates of Madhya Pradesh
will be able to do choice filling and choice locking for allotment.

12.
Candidates are advised to write down the details of their choice colleges in
advance before entering their choices so that they do not face any dilemma
while filling their choices on the portal. Candidates are expected to choose
the colleges for allotment after thinking carefully and keeping in mind the
fees displayed in different colleges and narrow down the selection to colleges.

13.
Candidates should ensure to lock their choices after filling any phase of
choice. In case the choice is not locked, the filled choice will not be valid
and the candidate will not be eligible for allotment in that phase.

14. Only
the children of persons working/retired/deceased/disabled in war in the three
wings of the Army, Army, Navy and Air Force are eligible for reservation.

15.
Students of Madhya Pradesh state will be eligible for 5 percent reservation
under the government school student category, who have passed regular studies
and examination from class 6th to 12th from a government school run by the
Madhya Pradesh government or from class 1 through the Right to Education Act.
After studying in private schools till 8th, must have completed regular studies
and examination from class 9th to 12th in a government school.

16. At the
time of registration, the candidate can select only one option as per his
eligibility from among the category disabled, soldier, freedom fighter and
government school student.

17. After
the release of allotment result, the candidate will be able to download the
allotment letter from his login ID and take its print out.

18. At the
time of admission, the allotted candidate should present himself in the
allotted institution for verification of records along with the original
documents mentioned in Form-1. The allotted candidate should first appear in
person at the allotted institution for admission within the declared time limit
(counselling time table) and register his attendance online by reporting at the
desk of the Government Nodal Officer. After that, get your original documents
verified by the appointed admission committee of the allotted institution. The
list of original documents is as per Schedule-3 attached with Madhya Pradesh
Medical Education Admission Rules 2018 and Format-1 of scrutiny of records is
available on the website of the Directorate and MP online portal. The candidate
will have to submit all his original documents to the admission committee. Make
sure to obtain the signed certificate of submission of original documents from
the head of the institution. After fee payment, the candidate will receive
online admission slip.

19. The
admitted candidate who wants to give the option of better option (upgradation)
for the second phase counselling will be able to log the option from the
upgradation option link available in his candidate login. If a candidate
admitted in the first phase wants the option of upgradation in the mop up
phase, then it will be mandatory for him to do choice filling in the second
phase while giving the option of upgrade after the first phase.

20. Those
candidates who have given the option of upgradation for second phase and/or mop
up phase will not have to submit Rural Service Bond and Seat Living Bond in
that phase. But to this effect he received Rs. Notarized affidavit of Rs.
500/-, in the name of the head of the admitted institution, that in case of
non-upgradation in the second phase/mopup phase, Gramin Seva bond and seat
living bond, separately duly stamped notarized affidavit, will be given in the
first phase. Must be submitted to the admitted institution.

21.
Certificate of disability issued from the designated NEET Disability
Certification Center for benchmark disability as per the criteria issued by
MCI/NMC for disability.

22.
Detailed information regarding various scholarship schemes of the government is
available on the website of the Directorate and M.P. Available on online
portal.

FREQUENTLY ASKED QUESTIONS for Madhya
Pradesh State Level Joint U.G. Counselling NEET UG 2024

Question
1- What will be the eligibility for admission to NRI quota seats in private
medical/dental colleges of the state?

Answer- It
is mandatory for the candidate to have secured the minimum percentile
prescribed by MCI for unreserved category in the selection examination of NEET
UG 2024, which is 50th percentile or more. Apart from this, the candidate
should be eligible as per Rule 2 (b) of Madhya Pradesh Medical Education
Admission Rules 2018 published in Madhya Pradesh Gazette dated 09 March 2018.

Question
2- Is NRI candidate eligible for open category seats in addition to NRI quota
seats?

Answer-
NRI candidates are also eligible for allotment on unreserved seats of open
category as per their eligibility/merit.

Question
3- Is reservation applicable on NRI quota seats?

Answer –
All the vacancies of NRI quota attached Schedule-2 section of Madhya Pradesh
Medical Education Admission Rules 2018 published in Madhya Pradesh Gazette
dated 09 March 2018 will be unreserved. – S, according to in Madhya Pradesh
Gazette dated 09 March 2018.

Question
4- Will NRI candidates have to register separately for NRI quota seats?

Answer-
NRI candidates will have to do only one registration for NRI quota seats.

Question 5-
If I do not take admission on the seat allotted to me in the first round of
counselling, will I be eligible for the subsequent rounds of counselling or
not?

Answer – If
you do not take admission on the allotted seat in the first phase of
counselling, you will remain eligible for the subsequent rounds of counselling.

Question
6- Are sons/daughters of persons working in Paramedical Force (BSF, CRPF, etc.)
also eligible for 3 percent horizontal reservation in military category?

not answer-
Only the children of persons working/retired/deceased/disabled in war in the
three wings of the Army, Army, Navy and Air Force are eligible for reservation.

Question 7- What is the eligibility for 5 percent horizontal
reservation for government school student category?

Answer- Students of Madhya Pradesh state will be eligible
for 5 percent reservation under the government school student category, who
have passed regular studies and examination from class 6th to 12th from a
government school run by Madhya Pradesh government or from class 1st to 8th
through the Right to Education Act. After studying in private schools, must
have completed regular studies and examinations from class 9th to 12th in a
government school.

Question 8- Can a candidate avail the benefits of more than
one category if he is eligible for more than one category at the time of
registration?

Answer- No. At the time of registration, the candidate will
be eligible under the category of disabled, soldier, freedom fighter and
government school student.

Can select only one option accordingly.

Question 9- I have not been allotted any seat in the first
phase of counselling. Will I be eligible for the second phase of counselling?

Answer- If no seat is allotted in the first phase
counselling, you will be eligible for the second phase counselling.

Question 10- Is the option of upgradation in state level
counselling available only after admission in the first phase?

Answer- Candidates admitted in state level counselling have
the facility of being given the option of upgradation after admission in the
first and or second phase of counselling.

Question 11- How can I opt for an upgrade?

Answer- Candidates can opt for upgradation from the
upgradation option available in their candidate profile.

Question 12- I have taken admission on the seat allotted in
the first phase of counselling, and at the time of admission, I have given the
option of upgradation for the second phase, then in case of no upgradation,
will my previous seat remain the same or not?

Answer- If you have taken admission on the seat allotted in
the first phase of counselling, and have given the option of upgradation and
you are not upgraded in the second phase, then in such a case your admitted
seat in the first phase will remain the same.

Question 13- I have taken admission on the seat allotted in
the second phase of counselling, and at the time of admission, I have given the
option of upgradation for mop up phase, then in case of no upgradation, will my
previous seat remain the same or not?

Answer – If you have taken admission on the allotted seat in
the second phase of counselling, or you have taken admission in the first phase
of counselling and have given the option of upgradation and you are not
upgraded in the mop up phase, then in such a case your first phase/second phase
counselling will be cancelled. Charan’s entered seat will remain the same.

Question 14- I have taken admission on the seat allotted by
me in first stage or second stage counselling, and at the time of admission I
have given the option of upgradation for second stage or mop up stage, then in
case of upgradation, will I be given the upgraded seat/college/category? Will
it be mandatory to take admission?

Answer- In case of upgradation in second stage or mop up
stage in the sequence of being given the option of upgradation, it is mandatory
for you to take admission in the upgraded seat/college/category. If the subject
or category is upgraded in the previously admitted college, it is mandatory for
the candidate to repeat the admission process in the same college. On
upgradation during the online upgradation process, the previously admitted seat
of the candidate gets automatically cancelled and is allotted to another
eligible candidate as per merit.

Question 15- What will be the procedure for resigning from
the admitted seat?

Answer: Resignation from the admitted seat will be subject
to sub-rule 1 of admission rule-15 and the process of submitting resignation is
online. Online resignation from the admitted seat will be done at the admitted
college level. It will be mandatory for the candidate to physically present
himself at the admitted college for the resignation process.

Question 16- If I take admission on the seat allotted in the
first phase of counselling, and resign from that seat, will I be eligible for
the subsequent rounds of counselling?

Answer- After taking admission in the allotted seat of the
first phase, if you resign from the seat under admission rule 15 sub rule 1,
then you will be eligible for all the subsequent stages of counselling.

Question 17- If I take admission on the seat allotted in the
first phase of counselling and resign from that seat within the shown time
period, then how much educational fee will I get refunded?

Answer – If you resign till two days before the second phase
of counselling, then after deducting 10 percent of your deposited fees (maximum
ten thousand rupees) your fees will be returned after the end of counselling.
If an NRI candidate resigns within the above mentioned time limit, a deduction
of Rs 25,000/- will be made.

Question 18- When will the seat living bond be applicable on
resignation from the admitted seat?

Answer- As per rules, seat leaving bond will not be
applicable if resignation is given till two days before the counselling of mop
up, but if resignation is given after the prescribed time limit, seat leaving
bond will be applicable.

Question 19- What will be the eligibility of the candidate
to participate in the second phase?

Answer- Eligibility will be determined according to sub-rule
2 of Admission Rule 11 (Madhya Pradesh Medical Education Admission Rules
2018-Amendment 2 July 2024).

Question 20- Will it be mandatory to do choice filling and
locking again to participate in second stage/mop stage?

Answer – To participate in the second phase / mop phase, it
will be mandatory for all eligible candidates to do choice filling and choice
locking after depositing the prescribed advance fee.

Question-21 How will the advance fee deposited in the second
phase/mop up phase be adjusted?

Answer – In case the seat is allotted in the second
phase/mop up phase, this amount will be adjusted in the total educational fee
of the allotted institution at the time of admission. If no seat is allotted in
the second phase/mopup phase, then this amount will be returned to the bank
account of the candidate within the stipulated time limit, but the candidates
who are allotted any seat in the second phase/mopup phase and they get
admission on the allotted seat. If the candidate does not take it, then the advance
fee deposited by the candidate will be confiscated.

Question-22: I am a candidate admitted through the first
phase of counselling and I have given the option of upgradation for the second
phase/mop up phase. In such a situation, can I resign from the admitted seat?

Answer- Yes.

Question-23 Will the registration process be done only once?

Answer- The registration process will be done as per the
schedule declared before counselling. After the second phase and before the mop
up phase, the registration process will be opened once again. Candidates
registered before the first phase of counselling are not eligible for
re-registration.

Question 24 What will be the eligibility for mop up phase?

Answer- Eligibility for mop up phase will be as follows-

1. Such candidates to whom allotment order has not been
issued in the first and second round of counselling.

2. Such candidates who have taken admission in the first or
second phase of counselling after allotment and have selected the better option
(upgradation).

3. Newly registered candidates.

Question 25- What does an eligible candidate have to do at
the mop up stage?

Answer- Such candidates will have to deposit Rs 2.00 lakh as
advance fee before choice filling and locking for mop up stage and NRI
candidates will have to deposit Rs 10 lakh as advance fee, only then they will
be able to do choice filling and choice locking.

Question 26- How will the advance fee of Rs 2.00 lakh / Rs
10 lakh (NRI candidates) be adjusted for mop up stage?

Answer: In case the seat is allotted, this amount will be
adjusted in the total educational fee of the allotted institution at the time
of admission. If no seat is allotted in the mop up round, then this amount will
be returned to the bank account of the candidate within the stipulated time
limit, but if the candidate who is allotted a seat in the mop up round does not
take admission on the allotted seat, then In this case, the advance fee
deposited by the candidate will be Rs. 2.00 Lakh / Rs. 10 Lakh.

Question 27- I was allotted a first choice seat from NRI
quota in the first phase, I have taken admission on it, now I want to take
admission in another college in the second phase, is this possible?

Answer- For this, after admission in the first phase, the
option of upgradation will have to be given on the candidate login and choice
filling and locking will have to be done again in the second phase of
counselling.

Question 28- Are candidates from outside Madhya Pradesh
eligible for NEET UG counselling 2024?

Answer – In case of local/native candidates of Madhya
Pradesh are not available in the merit in the second phase and subsequent
phases, seats will be allotted to the candidates from outside the state on the
basis of merit cum choice.

Question 29- I am a candidate of Scheduled Caste/Scheduled
Tribe/Other Backward Class, how will I get the benefit of reservation.

Answer- Those candidates who are eligible for reservation
under Scheduled Caste/Scheduled Tribe/Other Backward Class as defined in Madhya
Pradesh Medical Education Admission Rules 2018 will get the benefit of
reservation under Schedule-2.

Question 30- What do I have to do in case I get allotted a
seat in the counselling stage?

Answer – If you are allotted a seat in any phase of
counselling, then the candidate should go to the allotted college with the
necessary documents for admission mentioned in Schedule-3 along with a copy of
the allotment order. The process of admission is as per point number of Madhya
Pradesh Medical Education Admission Rules 2018. Must be completed within the
time limit of 10. The admission process can be completed only after depositing
the full academic fee through online process.

Question 31- Will I have to be present in the college for
registration/choice filling?

Answer- Registration and choice filling is an online
process. Candidates will be able to do both these processes from any place
through internet on the portal of MP Online. The candidate needs to appear in
the college for the admission process only after receiving the allotment order.

Question 32- What is the minimum and maximum number of
choices required to be filled in choice filling?

Answer – In choice filling, it is mandatory to fill at least
one choice. The candidate can fill maximum all the choices. After choice
filling, candidates should ensure to lock the choice.

Question 33- Can I fill the option of better seat (upgrade)?

Answer: After admission in first phase/second phase, the
candidate can fill the option of better option (upgradation) through his
candidate login.

Question 34- How will the vacant seats be allotted after the
mop up round?

Answer – After the mop up round, the allocation of vacant
seats will be done as per Rule 13 of Madhya Pradesh Medical Education Admission
Rules 2018.

Question 34- How will the vacant seats be allotted after the
mop up round?

Answer – After the mop up round, the allocation of vacant
seats will be done as per Rule 13 of Madhya Pradesh Medical Education Admission
Rules 2018.

Question 35- Which website do I have to use for counselling
process/guidelines?

Answer- The entire process of counselling will be done on portal. Apart from this, guidelines related to counselling
will be published on the website of Directorate of Medical Education. Candidates should be in constant touch with the
portal and website.

To view Advisory
for candidates & Frequently Asked Questions Click the link below

https://medicaldialogues.in/pdf_upload/student-advisory-ug-20247-247109.pdf

Powered by WPeMatico

Man arrested for impersonating doctor at Surat Hospital

Surat: A man in an intoxicated state has been recently arrested after being found posing as a doctor with a stethoscope hanging around his neck at New Civil Hospital in Surat.  

The accused, a resident of Sagrampura and a native of Maharashtra was caught red-handed by the security personnel after he was found roaming on the fourth floor of the kidney building which houses the medicine ward. Later, he was handed over to the police.  

Also read- Denied treatment at Chhattisgarh Hospital, 10-year-old boy dies; Drunk doctor faces suspension

As per The Indian Express news report, the incident took place on Friday when the nurse at the medicine ward of the hospital allegedly noticed the man roaming on the fourth floor wearing a stethoscope around his neck. After being suspicious of him, the nurse confronted him as she had never seen the man, as a doctor in the hospital before. After receiving an unsatisfactory response from the man, the nurse called the security guards and subsequently, he was taken to the office of the Medical Superintendent.  

According to the police, the accused had earlier worked as a male nurse at a private hospital. However, it is unclear why he was roaming in the hospital wearing a stethoscope in a drunken state.

Speaking to the Daily, Khatodara police inspector B R Rabari said, “We have done a medical examination of Shivaji Rao, 49, at the New Civil Hospital and found him to be drunk and arrested him. The accused had earlier worked as a male nurse in a private hospital but was jobless for the last few months. His wife still works at a private hospital in Surat. We are questioning him to find out the reason behind him walking in the hospital with a stethoscope.”

Also read- Rajkot Civil Hospital Gynaecologist caught in drunk state, Inquiry Ordered

Powered by WPeMatico

Low-Dose DOAC Offers Superior Balance of Efficacy and Safety Over DAPT After LAAO: ADALA Trial

Spain: In a new study published in JAMA Cardiology, the ADALA randomized clinical trial has unveiled new insights into post-procedural care following left atrial appendage occlusion (LAAO). The trial involving 90 participants compared the safety and efficacy of low-dose direct oral anticoagulation (DOAC) against dual antiplatelet therapy (DAPT) after LAAO procedures.

The findings suggest that low-dose direct oral anticoagulation may be a safe and effective antithrombotic therapy for patients following LAAO. The researchers found that low-dose DOAC demonstrated a more favorable balance of efficacy and safety compared to dual antiplatelet therapy after LAAO, with fewer device-related thrombotic events, comparable rates of thromboembolic events, and equivalent major bleeding risks.

The LAAO procedure reduces the risk of stroke in patients with atrial fibrillation who are at high risk of embolism. Traditionally, patients have been prescribed DAPT—typically a combination of aspirin and clopidogrel—to prevent thromboembolic events following the procedure. However, optimal antithrombotic therapy after percutaneous LAAO is not well established as no randomized evaluation has been performed to date.

Against the above background, Xavier Freixa, Department of Cardiology, Institut Cardiovascular, IDIBAPS, Hospital Clinic of Barcelona, Barcelona, Spain, and colleagues sought to compare the safety and efficacy of low-dose DOAC versus DAPT for three months after LAAO.

The ADALA study was an investigator-initiated, multicenter, prospective, open-label, randomized clinical trial. The trial began on June 12, 2019, across three European sites. It concluded prematurely on August 28, 2022, with only 60% of the targeted sample size enrolled due to slower recruitment rates caused by the COVID-19 pandemic.

Patients who underwent successful left atrial appendage occlusion were randomly assigned in a 1:1 ratio to receive either low-dose direct oral anticoagulation or dual antiplatelet therapy for three months following the procedure. The low-dose DOAC regimen consisted of apixaban, 2.5 mg, administered every 12 hours. The DAPT group was treated with aspirin, 100 mg daily, in combination with clopidogrel, 75 mg daily, for the same duration.

The study’s primary endpoint was a composite measure assessing safety and efficacy within the first three months following successful LAAO. This included major bleeding as the safety component and thromboembolic events—such as stroke, systemic embolism, and device-related thrombosis (DRT)—as the efficacy components. Secondary endpoints consisted of the individual components of the primary outcome, as well as all bleeding events.

The study led to the following findings:

  • The analysis included 90 patients (mean age, 76.6 years; 66.7% males; mean CHADS-VASc score, 4.0) (44 and 46 patients in the low-dose DOAC and DAPT groups, respectively).
  • 58.8% of patients presented with previous major bleeding events (66.7% gastrointestinal and 17.8% intracranial).
  • At three months, low-dose DOAC was associated with a reduction of the primary endpoint compared with DAPT (4.5% versus 21.7%; hazard ratio, 0.19).
  • Patients in the low-dose DOAC group exhibited a lower rate of DRT (0% versus 8.7%) and tended to have a lower incidence of major bleeding events (4.6% versus 13.0%), with no differences in thromboembolic events such as stroke and systemic embolism between groups (none in the overall population).

The findings indicate that low-dose DOAC usage for three months after LAAO offered a more favorable balance between efficacy and safety than DAPT. “However, given the limited sample size, these findings should be interpreted with caution and will require validation in future larger randomized trials,” the researchers concluded.

Reference:

Freixa X, Cruz-González I, Cepas-Guillén P, et al. Low-Dose Direct Oral Anticoagulation vs Dual Antiplatelet Therapy After Left Atrial Appendage Occlusion: The ADALA Randomized Clinical Trial. JAMA Cardiol. Published online August 07, 2024. doi:10.1001/jamacardio.2024.2335

Powered by WPeMatico

Fish Oil Use Linked to Lower Vascular Risks in Type 2 Diabetes Patients: Study

China: Regular consumption of fish oil supplements and elevated levels of omega-3 polyunsaturated fatty acids (PUFAs), particularly docosahexaenoic acid (DHA), are linked to reduced vascular complication risks in individuals diagnosed with type 2 diabetes (T2D), a recent study has found.

The findings, published in The Journal of Clinical Endocrinology & Metabolism, suggest that the positive correlations were partly explained by enhancements in lipid profile and reduction in inflammation biomarkers.

Fish oils, abundant in omega-3 polyunsaturated fatty acids (PUFAs), are recognized for their vascular health benefits in the general population. However, studies investigating their effects on individuals with type 2 diabetes (T2D), who face an elevated risk of vascular disease, are limited.

To fill this knowledge gap, Gang Liu, Huazhong University of Science and Technology, Wuhan, China, and colleagues aimed to evaluate associations of fish oil supplementation and plasma omega-3 PUFAs with risks of macrovascular and microvascular complications among people with type 2 diabetes. They further explored the potential mediating role of metabolism-related biomarkers.

This study comprised 20,338 participants with type 2 diabetes from UK Biobank. Participants’ use of regular fish oil supplementation was assessed through an electronic questionnaire administered at baseline from 2006 to 2010. Blood samples collected between 2019 and 2020 were analyzed for omega-3 fatty acids.

The study focused on diabetic macrovascular complications (including coronary heart disease, heart failure, peripheral artery disease, and stroke) and microvascular complications (such as diabetic kidney disease, diabetic retinopathy, and diabetic neuropathy). Biomarkers associated with cardiovascular disease were assessed in the blood samples obtained during recruitment.

The study revealed the following findings:

  • During 13.2 years of follow-up, 5,396 people developed macrovascular complications, and 4,868 people developed microvascular complications.
  • After multivariable adjustment, hazard ratios (HRs) for patients with fish oil were 0.90 for composite macrovascular complications, 0.91 for coronary heart disease (CHD), 0.72 for peripheral artery disease, and 0.89 for composite microvascular complications, 0.87 for diabetic kidney disease, and 0.88 for diabetic retinopathy.
  • Higher n-3 PUFA levels, especially docosahexaenoic acid (DHA), were associated with lower risks of macrovascular and microvascular complications. Comparing extreme quartiles of plasma DHA, the HRs were 0.68 for composite macrovascular complications, 0.63 for CHD, and 0.59 for diabetic neuropathy.
  • Biomarkers, including lipid profile and inflammation, collectively explained 54.4% and 63.1% of associations of plasma DHA with risks of composite macrovascular complications and CHD.

“Regular use of fish oil supplements and elevated plasma levels of omega-3 PUFAs, particularly DHA, were linked to reduced risks of macrovascular and microvascular complications in individuals with type 2 diabetes. The beneficial effects observed were partly attributed to improvements in lipid profile and reduction in inflammation biomarkers,” the researchers concluded.

Reference:

Tian, S., Guo, T., Qian, F., Qiu, Z., Lu, Q., Li, R., Zhu, K., Li, L., Yu, H., Li, R., Ou, Y., Pan, A., & Liu, G. Fish Oil, Plasma n-3 PUFAs, and Risk of Macro- and Microvascular Complications among Individuals with Type 2 Diabetes. The Journal of Clinical Endocrinology & Metabolism. https://doi.org/10.1210/clinem/dgae482

Powered by WPeMatico

Intermittent Calorie Restriction Enhances Cognitive Function and Memory in Older Adults, Pilot Study Shows

USA: An exploratory pilot study suggests that intermittent calorie restriction enhances executive function and memory in cognitively healthy older adults. The findings were published online in Cell Metabolism has revealed.

In an 8-week randomized clinical trial involving 40 overweight, cognitively healthy older adults with insulin resistance, researchers explored the impact of two different interventions on brain health. Participants were assigned to either a 5:2 intermittent fasting regimen—consisting of 2 days with a restricted intake of 480 calories per day (provided through meal replacement shakes) and five days of a healthy living diet based on portion control and calorie reduction guidelines—or a “healthy living” diet alone.

Both interventions improved executive function and memory, with intermittent fasting demonstrating superior results on specific cognitive measures, according to Dimitrios Kapogiannis, MD, from the National Institute on Aging (NIA) and Johns Hopkins University School of Medicine. The findings were presented in a poster at the Alzheimer’s Association International Conference. 

A diet may enhance brain health in older adults with metabolic impairments. Considering this, Dr. Kapogiannis and colleagues aimed to assess whether intermittent calorie restriction can reduce insulin resistance, enhance cognitive performance, improve brain metabolism and function, and normalize biomarkers associated with Alzheimer’s in adults aged 55 to 70.

The following were the key findings of the study:

  • While intermittent fasting led to more significant weight loss, both diets produced similar improvements in insulin signaling biomarkers in neuron-derived extracellular vesicles.
  • The researchers also showed comparable effects in reducing the brain-age-gap estimate (which reflects the rate of biological brain aging) on magnetic resonance imaging, lowering brain glucose levels on magnetic resonance spectroscopy, and enhancing blood biomarkers related to carbohydrate and lipid metabolism. Changes in cerebrospinal fluid biomarkers for Alzheimer’s disease were minimal.
  • Intermittent fasting and healthy living improved executive function and memory, and intermittent fasting benefited more certain cognitive measures.
  • In exploratory analyses, sex, body mass index, and apolipoprotein E and SLC16A7 genotypes modulated diet effects.

The study offers a framework for evaluating the impact of dietary interventions on brain health and encourages additional research into intermittent fasting and continuous diets for optimizing cognitive function, the researchers wrote.

The researchers noted that the trial’s short duration might have missed effects that developed beyond the 8 weeks. The study was sufficiently powered to detect only large or moderate effects over time and between the two interventions. They also acknowledged that some improvements in cognitive performance might be attributable to practice effects.

Reference:

Kapogiannis, D., Manolopoulos, A., Mullins, R., Avgerinos, K., Delgado-Peraza, F., Mustapic, M., Nogueras-Ortiz, C., Yao, P. J., Pucha, K. A., Brooks, J., Chen, Q., Haas, S. S., Ge, R., Hartnell, L. M., Cookson, M. R., Egan, J. M., Frangou, S., & Mattson, M. P. (2024). Brain responses to intermittent fasting and the healthy living diet in older adults. Cell Metabolism. https://doi.org/10.1016/j.cmet.2024.05.017

Powered by WPeMatico

Study Shows Plant Lignans, Found in Flaxseed, Whole Grains, and Coffee, May Reduce Type 2 Diabetes Risk

USA: New research reveals that a higher intake of lignans—plant compounds found in seeds, grains, and vegetables—is associated with a reduced type 2 diabetes (T2D) risk, particularly among individuals with obesity and premenopausal women.

The findings from 3 large prospective US cohorts, published in JAMA Network Open, suggest individual plant lignans appear to be beneficial in reducing the risk of type 2 diabetes, highlighting the importance of including lignan-rich foods—such as flaxseed products, whole grains, and coffee—in one’s diet for diabetes prevention.

Lignans, which are prevalent in flaxseeds, sesame seeds, whole grains, and certain vegetables, are known for their antioxidant and anti-inflammatory properties. Lignans are phytoestrogens commonly found in Western diets and may be linked to the risk of developing type 2 diabetes. Considering this, Siyue Wang, Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, and colleagues sought to prospectively investigate associations between lignan intake and incidence of type 2 diabetes.

For this purpose, the researchers conducted a population-based cohort study using data from various studies, including the Nurses’ Health Study (NHS, 1984-2018), NHSII (1991-2019), and the Health Professionals Follow-Up Study (HPFS, 1986-2020), along with 496 participants from the Men’s Lifestyle Validation Study (MLVS). All participants were free of T2D, cardiovascular disease, and cancer at the study’s outset. Data analysis took place between November 2022 and July 2023.

Lignan intake was evaluated through a validated food frequency questionnaire, which participants updated every 2 to 4 years. In the MLVS, lignan consumption was recorded using two sets of 7-day diet records.

The study identified new cases of T2D based on the American Diabetes Association diagnostic criteria. Cox proportional hazard models were employed to examine the associations between lignan intake and T2D, adjusting for multiple variables.

The study revealed the following findings:

  • The current study included 201 111 participants (mean age, 44.7 years; 80.2% female participants) from the HPFS, NHS, and NHSII studies. The median total lignan intake of the highest quintile ranged from 355.1 μg/d in NHS to 459.9 μg/d in HPFS at the median follow-up time.
  • 20,291 incident cases of T2D were identified over 5 068 689 person-years.
  • Higher lignan intake was inversely associated with T2D incidence, except for lariciresinol.
  • The multivariable-adjusted pooled hazard ratios (HRs) for the highest vs lowest quintiles were 0.87 for total lignans, 0.72 for secoisolariciresinol, 0.92 for pinoresinol, 0.93 for matairesinol, and 0.99 for lariciresinol.
  • Secoisolariciresinol intake exhibited a significant inverse association with T2D risk among individuals with obesity (HR, 0.75 for body mass index [BMI] ≥30 versus HR, 0.82 for BMI <25) and premenopausal women (HR, 0.67 for premenopausal women versus HR, 0.82 for the past use of hormones).
  • Dietary lignan assessed with 7DDRs was associated with lower HbA1c levels, as well as lower C-reactive protein levels and better lipid profiles.

The findings suggest that higher overall lignan intake, particularly from secoisolariciresinol, matairesinol, and pinoresinol (but not lariciresinol), is significantly linked to a lower risk of type 2 diabetes. The protective effect of secoisolariciresinol was notably more pronounced among individuals with obesity and premenopausal women.

“These results highlight the importance of a plant-based diet rich in lignan-containing foods, such as flaxseed products, whole grains, and coffee, for the primary prevention of type 2 diabetes,” the researchers concluded.

Reference:

Wang S, Hu Y, Liu B, Li Y, Wang M, Sun Q. Lignan Intake and Type 2 Diabetes Incidence Among US Men and Women. JAMA Netw Open. 2024;7(8):e2426367. doi:10.1001/jamanetworkopen.2024.26367

Powered by WPeMatico

Novel PET imaging tool identifies early signs of IBD and predicts response to treatment, suggests study

A newly developed imaging method, granzyme B PET, can non-invasively detect inflammatory bowel disease (IBD) and provide a real-time picture of active inflammation in the tissue, according to new research published in the July issue of The Journal of Nuclear Medicine. Information garnered from the PET images can be used to monitor IBD treatment efficacy and could potentially guide more personalized patient management strategies in the future.

IBD is a chronic gastrointestinal inflammatory disorder and includes two major groups: Crohn’s disease and ulcerative colitis. Although there have been notable advancements in the clinical management of IBD, substantial challenges remain in enhancing diagnostic precision, overcoming issues with treatment intolerance, and addressing the recurrent cycle of remission and relapse. In addition, long-standing IBD is associated with an increased risk of cancer, which necessitates constant monitoring of disease activity.

“Currently, there is no accurate method to detect and differentiate active inflammation from chronic disease. MRI and CT look at the structural changes in the bowel, while other imaging techniques look at the increased number of immune cells in the

tissue. None of the tools, however, capture the dynamic nature of immune responses in the colon,” said Pedram Heidari, MD, radiologist and service chief of nuclear medicine at Massachusetts General Hospital, Harvard Medical School, in Boston, Massachusetts. “A non-invasive imaging method to detect immune system activation with high resolution is key to improving IBD management.”

In the study, Heidari and colleagues assessed the potential of the granzyme B gene as a biomarker for detecting IBD and predicting treatment response. Human tissue samples of Crohn’s disease and ulcerative colitis (both active and inactive disease), as well as of the noninflamed bowel, were stained to measure the expression of granzyme B. Compared to noninflamed bowel tissue, granzyme B was upregulated significantly in diseased tissues, with active disease recording higher levels of granzyme B than inactive disease. Tissue samples from IBD treatment responders and non-responders were also measured, and lower granzyme B expression was found in the responders than the non-responders.

Next, the researchers evaluated changes in granzyme B expression in a murine model including colitis-induced and control mice. Mice were imaged with 68Ga-NOTA-GZP PET at one, three, and four weeks. PET imaging showed significantly increased bowel uptake of 68Ga-NOTA-GZP in mice induced with colitis versus control mice. After treatment, 68Ga-NOTA-GZP uptake in colitis-induced mice decreased, however, the uptake in colitis-induced mice remained significantly higher than the control at all times.

“Granzyme B PET can help with the timely detection of the active disease, determination of the need to start treatment, and monitoring the response to treatment to ensure the resolution of the inflammation. This is particularly important for monitoring inflammation in the parts of the bowel that are not accessible for endoscopy and tissue sampling,” stated Heidari. “This is a unique tool that can significantly change the trajectory of disease by closely monitoring treatment efficacy and is the true definition of precision medicine.”

Reference:

Pedram Heidari, Arvin Haj-Mirzaian, Suma Prabhu, Bahar Ataeinia, Shadi A. Esfahani and Umar Mahmood, Granzyme B PET Imaging for Assessment of Disease Activity in Inflammatory Bowel Disease, Journal of Nuclear Medicine, DOI: https://doi.org/10.2967/jnumed.123.267344.

Powered by WPeMatico